Associate Director / Director of Translational Biology

Discovery biology · Cambridge, Massachusetts
Department Discovery biology
Employment Type Full-Time

Associate Director / Director of Translational Biology


Remix Therapeutics is a biopharmaceutical company developing small molecule therapies focused on the emerging field of modulating RNA processing. Founded in 2019, Remix is building a highly collaborative team of experienced researchers to discover and develop life-changing therapies in areas of unmet medical need. The company is financed by Atlas Venture, The Column Group, Foresight Capital, Arch Venture Partners, and Alexandria Venture Investments.


Position Summary:

We seek a highly motivated biologist to join our growing team in Cambridge, MA. This position will report to the Senior Vice President of Translational Biology and will responsible for co-leading a multidisciplinary team tasked with driving an early drug discovery program to the clinic.  As Remix is exploring multiple therapeutic areas, experience in diverse disease biology is desirable, including oncology, rare genetic diseases and neurodegenerative disorders.  The role will involve both direct management of junior scientists, as well as management of external (CRO) resources.  The ideal candidate will have a strong background in translational biology and drug discovery and will be driven to succeed within a hypothesis-driven, team-oriented, and interdisciplinary biotech environment. Oncology experience is a must. The individual will be expected to contribute to all stages of drug discovery programs, advancing small molecules from hit identification to development candidate selection.


Principal Duties and Responsibilities

  • Co-lead interdisciplinary project teams and work with a team of scientists to progress projects from target selection and validation through candidate selection
  • Work with the project team to devise a robust and efficient LO cascade, including relevant cellular and in vivo models
  • Work with a project team to drive multiparametric lead optimization of small molecule therapeutics
  • Coordinate both internal and external (CRO) activities supporting programmatic drug discovery activities
  • Collaborate with key stakeholders to devise early clinical development path, including biomarker strategy and opportunities for accelerated approval.
  • Interface with external KOLs for input on disease hypothesis, translational models, clinical and regulatory landscape
  • Possess a clear and effective communication style
  • Build and maintain productive relationships with colleagues in chemistry, biomolecular sciences, and DMPK
  • Contribute to building the translational biology infrastructure and developing our innovative drug discovery platform


Qualifications

  • PhD. in cell biology, molecular biology, genetics or a related field
  • 8+ years of experience in an industry setting
  • Strong publication record and proven track record of success
  • Previous experience in managing both people and projects
  • Previous experience in managing external resources (CROs) is strongly preferred
  • Experience in multiple therapeutics is preferred. These include oncology, rare genetic disease, metabolic disease and neurology
  • Ability to effectively communicate to diverse audiences
  • Keen attention to detail and a strong sense of urgency is required as is the desire and ability to work in a multi-disciplinary and team-focused environment

 

Remix values diversity and is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, marital or veteran status, genetic information, sexual orientation or any other legally protected status. Remix will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.


Note to Third Party Staffing Agencies: Please do not forward any agency resumes. Remix Therapeutics is not responsible for any fees related to resumes that are unsolicited.



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  • Location
    Cambridge, Massachusetts
  • Department
    Discovery biology
  • Employment Type
    Full-Time